Endocrine Abstracts

Background: The adrenal incidentalomas (AI), adrenal masses ≥10 mm in diameter incidentally detected, have increased their prevalence due to technological advances in imaging. The adrenalectomy is indicated in functioning adrenal tumors and in cases suspected of malignancy.Objectives: To analyze the characteristics of patients with AI and to evaluate the clinical outcome, in terms of evolution toward hypersecretion and significant growth, during fo...

Introduction: Gestational Diabetes Mellitus (GDM) has been associated with complications both in the neonate and in the mother; including increased risk of Type 2 Diabetes Mellitus (DM2), obesity, and cardiovascular disease. Fibroblast growth factor 21 (FGF21) is a key regulator of glucose and lipid metabolism. Recently, the relationship between FGF21 and metabolic component diseases such as diabetes mellitus and obesity has been demonstrated. In addition, FGF21 mRNA and prote...

Objective: To study the association between genes codifying for mitochondrial respiratory chain (MRC) subunits and BMI and obesity as well as the impact on the risk to develop type 2 diabetes in the general population from Spain.Research design and methods: Three thousand seven hundred and thirty-one subjects (age range 21–89) from three different population-based studies of Spain, were studied. Forty-eight single nucleotide polymorphisms (SNPs) of ...